Risk for GERD higher with GLP-1 RA use compared to SGLT-2 inhibitor use: Study

A population-based cohort study emulating a target trial estimated the effect of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) compared with sodium-glucose cotransporter-2 (SGLT-2) inhibitors on the risk for gastroesophageal reflux…

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Anticholinergic Use Linked to Faster Physical Decline in Older Adults, finds research

Researchers have found in a new cohort study that higher exposure to anticholinergic medications was associated with an accelerated decline in physical performance. This decline was clinically meaningful, highlighting the…

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Semaglutide and Tirzepatide May Lower Dementia, Stroke, and Death Risk in Diabetic Patients With Obesity: Study

Taiwan: A large-scale cohort study published in JAMA Network Open suggests that the use of GLP-1 receptor agonists, specifically semaglutide and tirzepatide, may offer protective benefits beyond blood sugar control…

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Stress Hyperglycemia Ratio Identified as Predictor of Early Mortality in Acute CV Disease: Study

A new study published in the journal of BMC Cardiovascular Diabetology revealed that an elevated stress hyperglycemia ratio (SHR) is linked to increased early mortality in cardiovascular disease patients, even…

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Greater body roundness index among diabetes patients associated with Increased stroke risk: Study

A new study published in the journal of Diabetes Research and Clinical Practice showed that higher stroke risk is associated with greater body roundness index (BRI), particularly in people with…

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Palopegteriparatide Demonstrates Sustained 3-Year Efficacy in Hypoparathyroidism in Phase 3 trial

Researchers have found in a 3-year phase 3 trial that palopegteriparatide (TransCon PTH) showed sustained improvements in biochemical markers, kidney function, and quality of life in adults with hypoparathyroidism. Already…

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Vapes more effective for smoking cessation than nicotine gum and lozenges: Study

A randomized controlled trial (RCT) evaluated whether vaporized nicotine products (VNPs) are more effective than nicotine replacement therapies (NRT) for smoking cessation among people experiencing social disadvantage. The researchers found…

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Baxdrostat Significantly Lowers Blood Pressure in Resistant Hypertension in Phase 3 trial

AstraZeneca announced that baxdrostat, a selective aldosterone synthase inhibitor, met its primary and all secondary endpoints in the BaxHTN Phase III trial, effectively lowering blood pressure in patients with uncontrolled…

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